In the News
Coveted NIH Grant to Clinically Study Autologous Stem Cell Therapy for Parkinson’s Disease
Neuroregeneration Institute receives funding for clinical trials by NIH for autologous neurons in Parkinson's disease.
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Researchers find that lipid accumulation in the brain may be an early sign of Parkinson's disease.
Researchers find that lipid accumulation in the brain may be an early sign of Parkinson's disease
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How the gene behind Huntington’s disease could be neutralized
How anti-sense treatment for Huntington's disease started at the Neuroregeneration Laboratories Read
Previously in the News
Cell therapy from iPSC works in Parkinson's preclinical models confirmed | Alzforum. Read
Health and Medicine: A new era in Parkinson's disease treatments.
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Engelender and Isacson suggest new theory for how Parkinson's disease develops - ScienceDaily. Read
Fighting Parkinson's in the lab. Read
NPR interviews Dr. Isacson about Mohammed Ali's fight with Parkinson's disease. Listen
National Stem Cell Foundation and Michael J. Fox Foundation Partner to Support Parkinson's Cell Replacement Therapy. Read
MJFF Parkinson podcast with Dave Iverson and Ole Isacson 2016: The stem cells basics. Listen
Ole Isacson Lecture on Parkinson's disease in a Dish: Induced Pluripotent Stem Cell Models of Disease SFN Neurobiology of Disease Workshop graduate course. Watch
WMIF 2015 | Regeneration, Cell Therapy, and Neurocare: Products? Delivery? Watch
Nature Biotechnology reviews the use of iPSCs for drug discovery and modeling of familial Parkinson's disease in cell culture. Read
Ole Isacson - Keynote speech at Innovative Medicines Initiative (IMI) Stakeholder forum 2014. Watch
Long-term survival of dopamine neurons in patients: Encouraging news for future stem-cell based dopamine neuron transplant. Listen
Dr. Isacson Elected Fellow of The American Association for the Advancement of Science. Read
Dr. Isacson Presents Stem Cell Research at Vatican Conference in Rome. Read
Dr. Isacson Selected for Executive Scientific Advisory Board of the Michael J. Fox Foundation. Read
Getting Closer to a Stem Cell Therapy for Parkinson’s Disease. Read
Neuroregeneration Lab's Amyotrophic Lateral Sclerosis (ALS) Research Featured in New Video. Watch
Mitochondrial Energetics Energize Parkinson's Disease iPSC-derived Neural Study. Read
Personalized Medicine Closer to Reality. Read
PDiPS Consortium and Neuroregeneration Institute show cells from different patients have unique drug responses. Read
FRONTLINE: A Report on Parkinson's Disease
Update on PBS: June, 2012
Dr. Penny Hallett speaks about new PD research
2010 Southeastern Parkinson Disease Conference, October 16, 2010. Watch
Dr. Isacson speaks at the 2010 Parkinson Action Network Morris K. Udall Awards Dinner
Parkinson Action Network Official Site: Udall Dinner Highlights
Harvard Stem Cell Institute Monthly Update
December 2009. Read
HSCI Highlights Stem Cell Sorting Work at the Neuroregeneration Lab. Read
NINDS GO Grant funding awarded for PDiPS Cell Line Research Consortium. Read
Interview with Dr. Isacson. Read
Cozzarelli Prize Awarded
The Cozzarelli Prize recognizing recently published PNAS papers of outstanding scientific excellence and originality has been awarded to Wernig et al. 2008. This article is a shared collaborative work between the Harvard/McLean (Dr. Isacson's lab) and MIT (Dr. Jaenisch's lab). This is the first paper to show induction of stem cells from skin cells, then conversion to dopaminergic cells and successful functional testing in animal models of Parkinson’s disease.
Press Release from Eurekalert
Wernig et al. 2008 PDF File
FRONTLINE: A Report on Parkinson's Disease
Coming soon to PBS; Early 2009Video Highlights
Summit on Stem Cell Research and New Clinical Trials
Brain Repair Centre/Center for Neuroregeneration Research 2008:Press Release and Photo
Reprogrammed adult skin cells treat Parkinson's disease in animal model
HarvardScience Online; April 10, 2008Article Link
Stem Cells from Skin Treat Brain Disease in Rats
Reuters Online; April 7, 2008Article Link
Parkinson's Brain Cell Transplants Last for Years
Reuters Online; April 6, 2008Article Link
Partnership is a Real No-Brainer; Dal-Harvard to work together on brain repair
The Chronicle Herald; February 21, 2008Halifax Chronicle Herald, Feb. 21, 2008
Metro Newspaper, Feb. 21, 2008
Press Release
Neuron Connections May Be Key to Stemming Parkinson's Disease
McLean Hospital News; August 20, 2007Press Release
PDF File of Article
Discovering the strengths and weaknesses of the Dopamine neuron: The role of G-substrate
The Journal of Neuroscience; August 1, 2007Article Link
Development of new therapies for Parkinson’s disease (Interview with Ole Isacson)
JoVE, Issue 3, May 2007Link to Video Article
Spurring Protein Breakdown in Brain Cells Halts Huntington’s Pathology
The Harvard Focus Online; Published on March 9, 2007Article Link
Proteasome Activator Enhances Survival of Huntington's Disease Neuronal Model Cells
Alzheimer Research Forum; March 8, 2007Article Link
Stem Cell Work Shows Promise and Risks
The Washington Post; Published on October 23, 2006Article Link
PDF File of Article
Stem cell research targets Parkinson's
The Atlanta Journal-Constitution; Published on October 17, 2006
Press Conference at the 36th Annual Society for Neuroscience Meeting, Atlanta, GAPDF File of Article
HCNR News Website
4th Cellular and Molecular Treatments Conference
Sept. 29-30, 2006McLean Hospital Press Conference Link
Neuronal Stem Cells: A Long Road Ahead For Als, PD, And Glioblastoma Treatment
Neurology Today: Volume 6(14) 18 July 2006 p 15-16
PDF File of Article
The Promise and Pitfalls of Embryonic Stem Cells
September 22, 2005
Article Link
Fetal-cell Transplants Reverse Parkinson’s in Patients
June 10, 2005, Harvard Focus
Article Link
Clinical study results in Parkinson's patients may lead to development of future stem cell transplantation methodsMay 5, 2005 Michael J. Fox Foundation Press
Huntington's Defects Manifest Far from Damaged Brain Tissue
September 3, 2004, Harvard Focus
http://focus.hms.harvard.edu/2004/Sept3_2004/neurology.html
Huntington's disease multiple cell abnormalities and adaptive mechanisms Reuters Health InformationPDF file of article
HD gene product alters protein handling in patient's skin and brain, with complex toxic effects only in the most vulnerable brain cellsJuly 23, 2004, Press Release, EurekAlert!
http://www.eurekalert.org/pub_releases/2004-07/jws-eoh071904.php
New study on Huntington's disease reveals pathology and new treatment options
July 30, 2004, McLean Hospital Press Release
http://www.mclean.harvard.edu/news/press/current.php?id=58
The Scientist recognizes Harvard/McLean Parkinson's Disease Udall Center's contribution on ES cells.
Embryonic Stem Cells WorkJune 21, 2004, The Scientist
http://www.the-scientist.com/yr2004/jun/hot_040621.html
PDF file of article
US Stem Cell Research LaggingSunday, May 23, 2004, The Boston Globe
Article from the Boston Globe
PDF file of article
Stem Cell work for Parkinson's Disease at the Neuroregeneration LabSunday, February 29, 2004, The Boston Globe
PDF file of Article from the Boston Globe
Harvard Wide Initiative for Stem Cell ResearchSunday, February 29, 2004, The Boston Globe
PDF file of Article from the Boston Globe
Professor Ole Isacson interviewed: Harvard's latest work on embryonic stem cells for Parkinson's disease
Friday, March 12, 2004, Grassroots Connection
Article from Grassroots Connection
Gene therapy used to treat patient with Parkinson's
Tuesday, August 19, 2003, The New York Times
Abstract from NY Times Archive
Article from NY Times
The production and use of cells as therapeutic agents in neurodegenerative diseasesIsacson O. Lancet Neurology 2003 Jul;2(7):417-24.
Abstract from PubMed
Download PDF file
Enzyme Linked to Pathology of Parkinson's Disease Appears Two-faced. http://focus.hms.harvard.edu/2002/Nov8_2002/neurology.html
Stem Cell Hopes Double. http://www.nature.com/nsu/020617/020617-11.html